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Lines of Research

Lines of Research – Academic Master’s and Doctorate Degrees in Medicine and Biomedicine

Research Groups

GROUP I – NEUROLOGICAL DISEASES: GENETICS, PHYSIOPATHOLOGY AND EPIDEMIOLOGY

Topic 1: Genetic polymorphism in neurological diseases
Description: Determination of inter-populational genetic variations in pathologies of the central nervous system and their association with therapeutic response and disease severity.
Coordinator: Dr. Karla Simone da Silva Fernandes

Topic 2: Biomarkers in cerebrovascular diseases
Description: Utilization of biomarkers in clinical practice with the aim of evaluating the diagnosis and evolution of medical treatment of strokes and traumatic brain injuries.
Coordinator: Prof. Dr. Marcos Antônio Dellaretti Filho

Topic 3: Pathophysiology and therapy of multiple sclerosis
Description: Investigation of diseases of the central and peripheral nervous system using clinical, laboratory, anatomopathological and imaging resources in order to advance the understanding of pathophysiological mechanisms and therapies of degenerative diseases.
Coordinator: Dr. Paulo Pereira Christo

GROUP II – MOLECULAR MECHANISMS IN TUMORS

Topic 1: Differentiated thyroid cancer
Description: Investigation of clinical aspects of the treatment and follow-up of patients with differentiated thyroid cancer.
Coordinator: Dr. Pedro Weslley do Rosário Souza

Topic 2: Genetics of colorectal cancer
Description: Investigation of the clinical aspects of patients with colorectal cancer, of new conservative chemo- and radio-therapeutic treatments and alternative methods. Evaluation of the perioperative period of patients submitted to operations for the treatment of cancer.
Coordinator: Dr. Geraldo Magela Gomes da Cruz

Topic 3: Cancer associated with oncoviruses
Description: Analysis of the molecular alterations that occur in solid tumors of spontaneous, familial and oncovirus-associated (human papillomavirus, HPV) origin.
Coordinator: Dr. Renata Toscano Simões

GROUP III – DIABETES: PHYSIOPATHOLOGY, GENETICS, SIGNALING PATHWAYS AND EDUCATION

Topic 1: Diabetes and obesity
Description: Study of the pathological consequences of diabetes and obesity.
Coordinator: Dr. Adriana Aparecida Bosco

Topic 2: Diabetes education
Description: Development of processes, techniques and application of educational programs aimed at diabetes care, with a focus on the metabolic control and early identification of diabetic complications.
Coordinator: Dr. Janice Sepúlveda Reis
Note: Only available in the Doctorate Degree program

GROUP IV – SIGNALING PATHWAYS, MOLECULAR IMMUNOLOGY AND IMMUNOGENETICS

Topic 1: Metabolic signaling in innate immune cells
Description: Study of inflammation and its biomarkers, including changes in metabolic signaling in cells of the immune system.
Coordinator: Dr. José Augusto Nogueira Machado

GROUP V – HUMAN GENETICS

Topic 1: Pharmacogenetics
Description: Study of inter-populational genetic variations and its relationship with different types of drug response, especially regarding the pharmacokinetics and pharmacodynamics of the drugs.
Coordinator: Dr. Karla Simone da Silva Fernandes

GROUP VI – CARDIOLOGY

Topic: Biological and imaging markers
Description: Imaging analysis and assessment of biological markers in cardiovascular and pulmonary diseases.
Coordinator: Dr. Francisco das Chagas Lima e Silva

GROUP VII – EPIDEMIOLOGY

Topic: Epidemiology of aging and tumors
Description: Study of the demographic distribution of diseases (i.e. who gets sick, and where and when the disease occurs) and the conditions that determine the development of diseases in the human population, with the aim of identifying the risk factors associated with infection and illness, and of preventing these situations.
Coordinator: Dr. Carlos Maurício de Figueiredo Antunes

GROUP VIII – SURGERY

Topic: Wound healing
Description: Study of healing phenomena, including morphological, macro- and micro-scopic, functional (resistance, tension, protection, etc.) and aesthetic aspects, as well as the influence of extrinsic factors (nutritional and immunological status, age, use of medication, illnesses, etc.)
Coordinator: Dr. Luiz Ronaldo Alberti

GROUP IX – MYCOLOGY

Topic: Mycology: molecular basis of the taxonomy of pathogenic fungi
Description: Morpho-physiological and molecular characterization of human pathogenic fungi.
Coordinator: Dr. Rachel Basques Caligiorne

GROUP X – TOXINOLOGY

Topic 1: Pharmacology of poisons and toxins: cell signaling
Description: Study of the role of spider venom toxins in inhibiting neurotransmitter release by the central nervous system (CNS), and the effects of purified toxin peptides on pain and cardiac arrhythmias.
Coordinator: Dr. Marcus Vinicius Gomez

Topic 2: Neurophysiology and neuropharmacology of pain: cellular and molecular aspects
Description: Elucidation of the mechanism of action of animal toxins and other analgesic drugs, focusing on the spinal cord, neurons of the peripheral nervous system, calcium-mediated signaling pathways, release of neurotransmitters and the function of ion channels in pain transmission pathways.
Coordinator: Dr. Célio José de Castro Junior

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